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Year : 2022  |  Volume : 33  |  Issue : 1  |  Page : 1
Future Research in Oral Health

Executive Editor, Indian Journal of Dental Research, Director & Consultant Oral & Maxillofacial Surgeon, Balaji Dental and Craniofacial Hospital, Chennai, Tamil Nadu, India

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Date of Submission10-Jul-2022
Date of Acceptance12-Jul-2022
Date of Web Publication09-Aug-2022

How to cite this article:
Balaji S M. Future Research in Oral Health. Indian J Dent Res 2022;33:1

How to cite this URL:
Balaji S M. Future Research in Oral Health. Indian J Dent Res [serial online] 2022 [cited 2023 Jan 29];33:1. Available from:

The role of nitrate in maintaining the oral health has been recently discussed widely. It has been suggested the presence of optimal levels of nitrates in food and oral cavity can cause eubiosis, possibly reducing dental caries, ensuring optimal oral and general health and well-being.[1] Indian foods are known to be rich in nitrate sources and this aspect can be best explored.[2],[3] Recent technique upgrades in this direction, including rapid analytical devices that are environmentally friendly, microfluidic paper-based analytical device employing common, cheap beeswax as tool for simultaneous measurement of nitrate and nitrite in food products would be proving as a boon.[4]

There is a dearth of data on the optimum, Indian population-based levels of daily nitrate intake (both in diseased and healthy population especially the non-communicable disease (NCD) spectrum), long- and short-term effects of nitrate-based oral hygiene products or chewing tablets, effect of smoking/chewing tobacco on oral nitrate levels, correlation of serum/plasma markers of inflammation with oral nitrate levels, salivary flow and quality alterations with oral nitrate level, oral microbial characteristics in spectrum of nitrate levels. These would be very valuable.

Previous reports have associated the oral health with NCDs.[5] The emerging NCDs, particularly in Asia-Pacific region are worrisome.[6] From this perspective, besides oral health status, emerging Indian dietary pattern and emerging shift could be studied in total, addressing the dearth of data in Indian population in this aspect. Besides contributing to valuable data for Indian Salivary research core, the data could play an important role in combating the increasing NCD in the Indian subcontinent. Once the Indian subcontinent data could work on a hypothesis that oral microbiome of patients with different oral and systemic diseases have differences in their nitrate reduction capacity, as measured by an accurate, cheap and non-invasive diagnostic test, the results would be helpful to draw meaningful nutritional and oral health policies, not only for India but also for the entire world.

I suppose that this editorial would stimulate a range of Indian research and provide meaningful approach.

   References Top

Rosier BT, Takahashi N, Zaura E, Krom BP, MartÁnez-Espinosa RM, van Breda SG, et al. The importance of nitrate reduction for oral health. J Dent Res 2022;101:887-97.  Back to cited text no. 1
Gundimeda U, Naidu AN, Krishnaswamy K. Dietary intake of nitrate in India. J Food Compost Anal 1993;6:242-9.  Back to cited text no. 2
Hord NG, Tang Y, Bryan NS. Food sources of nitrates and nitrites: The physiologic context for potential health benefits. Am J Clin Nutr 2009;90:1-0.  Back to cited text no. 3
Thongkam T, Hemavibool K. An environmentally friendly microfluidic paper-based analytical device for simultaneous colorimetric detection of nitrite and nitrate in food products. Microchemical J 2020;159:105412. doi: 10.1016/j.microc. 2020.105412.  Back to cited text no. 4
Balaji SM. Oral microbes and NCDs. Indian J Dent Res 2019;30:331.  Back to cited text no. 5
[PUBMED]  [Full text]  
Balaji SM, Seeberger GK, Hennedige O. Burden of oral diseases and noncommunicable diseases: An Asia-pacific perspective. Indian J Dent Res 2018;29:820-9.  Back to cited text no. 6
[PUBMED]  [Full text]  

Correspondence Address:
S M Balaji
Executive Editor, Indian Journal of Dental Research, Director & Consultant Oral & Maxillofacial Surgeon, Balaji Dental and Craniofacial Hospital, Chennai, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdr.ijdr_541_22

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