Indian Journal of Dental Research

SHORT COMMUNICATION
Year
: 2020  |  Volume : 31  |  Issue : 6  |  Page : 963--966

Prevention of dental caries by regular overnight application of a low-concentration fluoride gel loaded in a custom tray in patients undergoing radiotherapy for head and neck cancer: A preliminary study


Sakiko Soutome1, Souichi Yanamoto2, Madoka Funahara3, Yumiko Kawashita4, Masako Yoshimatsu4, Maho Murata2, Toshiyuki Saito1, Masahiro Umeda2 
1 Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
2 Department of Clinical Oral Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
3 Kyushu Dental University School of Oral Health Sciences, Kitakyushu, Fukuoka, Japan
4 Oral Management Center, Nagasaki University Hospital, Nagasaki, Japan

Correspondence Address:
Dr. Souichi Yanamoto
Department of Clinical Oral Oncology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588
Japan

Background:</bold> Some studies have reported topical application of 1.0%–2.0% fluoride gel in a custom tray for 4–5 minutes every day for the prevention of radiation-related dental caries. However, in Japan, the concentration of fluoride used by patients is limited to less than 0.15%. The efficacy of a low-concentration fluoride gel in a custom tray for the prevention of radiation-related dental caries has not been investigated. <bold>Methods and Material:</bold> In this preliminary study, we enrolled 13 patients with head and neck cancer who underwent radiotherapy. They wore a custom tray containing 0.145% sodium fluoride gel during sleep every night and were examined for newly developed dental caries 1 year later. <bold>Results:</bold> No new dental caries were found in the 13 patients 1 year after radiotherapy, and no adverse events were observed. <bold>Conclusions:</bold> We conclude that low-concentration fluoride gel in a custom tray during sleep could prevent radiation-related dental caries, and we plan to conduct a multi-center phase III randomized controlled trial to examine the efficacy of this method for the prevention of radiation-related dental caries.


How to cite this article:
Soutome S, Yanamoto S, Funahara M, Kawashita Y, Yoshimatsu M, Murata M, Saito T, Umeda M. Prevention of dental caries by regular overnight application of a low-concentration fluoride gel loaded in a custom tray in patients undergoing radiotherapy for head and neck cancer: A preliminary study.Indian J Dent Res 2020;31:963-966


How to cite this URL:
Soutome S, Yanamoto S, Funahara M, Kawashita Y, Yoshimatsu M, Murata M, Saito T, Umeda M. Prevention of dental caries by regular overnight application of a low-concentration fluoride gel loaded in a custom tray in patients undergoing radiotherapy for head and neck cancer: A preliminary study. Indian J Dent Res [serial online] 2020 [cited 2022 Jul 5 ];31:963-966
Available from: https://www.ijdr.in/article.asp?issn=0970-9290;year=2020;volume=31;issue=6;spage=963;epage=966;aulast=Soutome;type=0