Figure 2: A study subject from Group A subjected to diagnostic test (Lugol's iodine + chemiluminescence) and reference standard (histopathology), The clinical diagnosis of the lesion was speckled leukoplakia in relation to left buccal mucosa. The decreased uptake of Lugol's iodine stain with enhanced acetowhite hue is seen using chemiluminescence. Histopathology is suggestive of hyperparakeratosis with moderate epithelial dysplasia